Protective Effects of Therapeutic Neutrophil Depletion and Myeloperoxidase Inhibition on Left Ventricular Function and Remodeling in Myocardial Infarction

• Main Authors: Henning Guthoff (Author), Alexander Hof (Author), Anna Klinke (Author), Martina Maaß (Author), Jürgen Konradi (Author), Dennis Mehrkens (Author), Simon Geißen (Author), Felix S. Nettersheim (Author), Simon Braumann (Author), Erik Michaelsson (Author), Richard J. Nies (Author), Samuel Lee (Author), Marie-Christin Redzinski (Author), Vera B. M. Peters (Author), Harshal N. Nemade (Author), Philipp von Stein (Author), Holger Winkels (Author), Volker Rudolph (Author), Stephan Baldus (Author), Matti Adam (Author), Martin Mollenhauer (Author)
• Format: Bog
• Udgivet: MDPI AG, 2022-12-01T00:00:00Z.
• Fag: article
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Myocardial infarction (MI) is a leading cause of morbidity and mortality worldwide. Improved survival has led to an increasing incidence of ischemic cardiomyopathy, making it a major reason for hospitalization in the western world. The inflammatory response in the ischemic myocardium determines the...