A Marine Analgesic Peptide, Contulakin-G, and Neurotensin are Distinct Agonists for Neurotensin Receptors: Uncovering Structural Determinants of Desensitization Properties

• প্রধান লেখক: Hee-Kyoung eLee (লেখক), Liuyin eZhang (লেখক), Misty D Smith (লেখক), Aleksandra eWalewska (লেখক), Nadeem eVellore (লেখক), Riccardo eBaron (লেখক), J Michael eMcIntosh (লেখক), H Steve eWhite (লেখক), Baldomero M Olivera (লেখক), Grzegorz eBulaj (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Frontiers Media S.A., 2015-02-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Neurotensin receptors have been studied as molecular targets for the treatment of pain, schizophrenia, addiction, or cancer. Neurotensin (NT) and Contulakin-G, a glycopeptide isolated from a predatory cone snail Conus geographus, share a sequence similarity at the C-terminus, which is critical for a...