A phase I/II feasibility vaccine study by autologous leukemic apoptotic corpse-pulsed dendritic cells for elderly AML patients

• Main Authors: Patrice Chevallier (Author), Soraya Saiagh (Author), Virginie Dehame (Author), Thierry Guillaume (Author), Pierre Peterlin (Author), Sylvain Bercegeay (Author), Yannick Le Bris (Author), Céline Bossard (Author), Isabelle Gauvrit (Author), Brigitte Dreno (Author), Nadine Juge-Morineau (Author), Marie C. Béné (Author), Marc Gregoire (Author)
• Format: Book
• Published: Taylor & Francis Group, 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

This was a phase I/II study testing the feasibility of a vaccine by autologous leukemic apoptotic corpse-pulsed dendritic cells (DC) in elderly acute myeloid leukemia (AML) patients in first or second complete remission. Pulsed DC were administered at doses of 9 × 106 subcutaneously (1 mL) and 1 × 1...