Impact of the amount of PEG on prodrug nanoassemblies for efficient cancer therapy

• Egile Nagusiak: Yaqiao Li (Egilea), Lingxiao Li (Egilea), Qianhui Jin (Egilea), Tian Liu (Egilea), Jin Sun (Egilea), Yongjun Wang (Egilea), Zhijun Yang (Egilea), Zhonggui He (Egilea), Bingjun Sun (Egilea)
• Formatua: Liburua
• Argitaratua: Elsevier, 2022-03-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

PEGylation has been widely used to improve the pharmacokinetic properties of prodrug self-assembled nanoparticles (prodrug-SANPs). However, the impacts of the amount of PEG on the self-assemble stability, cellular uptake, pharmacokinetics, and antitumor efficacy of prodrug-SANPs are still unknown. H...