The involvement of the sigma-1 receptor in neurodegeneration and neurorestoration

The sigma-1 receptor (Sig-1R) is a single 25 kD polypeptide and a chaperone protein immersed in lipid rafts of the endoplasmic reticulum (ER) where it interacts with mitochondria at the mitochondria-associated ER membrane domain (MAM). Upon activation, the Sig-1R binds to the inositol trisphosphate...

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Main Authors: Karsten Ruscher (Author), Tadeusz Wieloch (Author)
Format: Book
Published: Elsevier, 2015-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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