The involvement of the sigma-1 receptor in neurodegeneration and neurorestoration
The sigma-1 receptor (Sig-1R) is a single 25 kD polypeptide and a chaperone protein immersed in lipid rafts of the endoplasmic reticulum (ER) where it interacts with mitochondria at the mitochondria-associated ER membrane domain (MAM). Upon activation, the Sig-1R binds to the inositol trisphosphate...
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| Main Authors: | , |
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| Format: | Book |
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Elsevier,
2015-01-01T00:00:00Z.
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