Pharmacokinetics of Caffeine: A Systematic Analysis of Reported Data for Application in Metabolic Phenotyping and Liver Function Testing

• Main Authors: Jan Grzegorzewski (Author), Florian Bartsch (Author), Adrian Köller (Author), Matthias König (Author)
• Format: Bog
• Udgivet: Frontiers Media S.A., 2022-02-01T00:00:00Z.
• Fag: article
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Caffeine is by far the most ubiquitous psychostimulant worldwide found in tea, coffee, cocoa, energy drinks, and many other beverages and food. Caffeine is almost exclusively metabolized in the liver by the cytochrome P-450 enzyme system to the main product paraxanthine and the additional products t...