Glibenclamide for the Treatment of Acute CNS Injury

• Hauptverfasser: J. Marc Simard (Verfasst von), Nicholas M. Caffes (Verfasst von), Volodymyr Gerzanich (Verfasst von), Jason K. Karimy (Verfasst von), Adam Pampori (Verfasst von), Cigdem Tosun (Verfasst von), David B. Kurland (Verfasst von)
• Format: Buch
• Veröffentlicht: MDPI AG, 2013-10-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

First introduced into clinical practice in 1969, glibenclamide (US adopted name, glyburide) is known best for its use in the treatment of diabetes mellitus type 2, where it is used to promote the release of insulin by blocking pancreatic KATP [sulfonylurea receptor 1 (Sur1)-Kir6.2] channels. During...