Convergent Synthesis of Two Fluorescent Ebselen-Coumarin Heterodimers

• मुख्य लेखकों: Jim Küppers (लेखक), Anna Christina Schulz-Fincke (लेखक), Jerzy Palus (लेखक), Mirosław Giurg (लेखक), Jacek Skarżewski (लेखक), Michael Gütschow (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2016-07-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

The organo-seleniumdrug ebselen exhibits a wide range of pharmacological effects that are predominantly due to its interference with redox systems catalyzed by seleno enzymes, e.g., glutathione peroxidase and thioredoxin reductase. Moreover, ebselen can covalently interact with thiol groups of sever...