Hesperetin-5,7,3'-O-triacetate suppresses airway hyperresponsiveness in ovalbumin-sensitized and challenged mice without reversing xylazine/ketamine-induced anesthesia in normal mice
Abstract Background We recently reported that hesperetin-5,7,3'-O-triacetate (HTA) dually inhibited phosphodiesterase (PDE)3/4 with a therapeutic ratio of 20.8. The application and development of PDE4 inhibitors for treating asthma or COPD are limited by their side effects, such as nausea, vomi...
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| Main Authors: | , , , |
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| Format: | Book |
| Published: |
BMC,
2017-05-01T00:00:00Z.
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| Call Number: |
A1234.567 |
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| Copy 1 | Available |