Standardized orthotopic xenografts in zebrafish reveal glioma cell-line-specific characteristics and tumor cell heterogeneity

• المؤلفون الرئيسيون: Alessandra M. Welker (مؤلف), Brian D. Jaros (مؤلف), Vinay K. Puduvalli (مؤلف), Jaime Imitola (مؤلف), Balveen Kaur (مؤلف), Christine E. Beattie (مؤلف)
• التنسيق: كتاب
• منشور في: The Company of Biologists, 2016-02-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Glioblastoma (GBM) is a deadly brain cancer, for which few effective drug treatments are available. Several studies have used zebrafish models to study GBM, but a standardized approach to modeling GBM in zebrafish was lacking to date, preventing comparison of data across studies. Here, we describe a...