Altered levels of memory T cell subsets and common γc cytokines in Strongyloides stercoralis infection and partial reversal following anthelmintic treatment.

• Main Authors: Anuradha Rajamanickam (Author), Saravanan Munisankar (Author), Yukti Bhootra (Author), Chandra Kumar Dolla (Author), Kannan Thiruvengadam (Author), Thomas B Nutman (Author), Subash Babu (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2018-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

CD4+ and CD8+ T cells are central players in immunity to helminth infections. However, the role of T cell subsets in human helminth infections is not well understood. In addition, the common γc cytokines, IL-2, IL-4, IL-7, IL-9 and IL-15 play an important role in the maintenance of these CD4+ and CD...