New dammarane-type triterpenoids from hydrolyzate of total Gynostemma pentaphyllum saponins with protein tyrosine phosphatase 1B inhibitory activity

• Main Authors: Daopeng Tan (Author), Jianmei Wang (Author), Xianting Wang (Author), Lin Qin (Author), Yimei Du (Author), Changkuo Zhao (Author), Peijun Liu (Author), Qianru Zhang (Author), Feifei Ma (Author), Jian Xie (Author), Di Wu (Author), Yuqi He (Author)
• Format: Book
• Published: Taylor & Francis Group, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Protein tyrosine phosphatase 1B (PTP1B) is a key factor and regulator of glucose, lipid metabolism throughout the body, and a promising target for treatment of type 2 diabetes mellitus (T2DM). Gynostemma pentaphyllum is a famous oriental traditional medicinal herbal plant and functional food, which...