An Analysis of the Expression and Association with Immune Cell Infiltration of the cGAS/STING Pathway in Pan-Cancer

• Автори: Xiang An (Автор), Yuanyuan Zhu (Автор), Tongsen Zheng (Автор), Guangyu Wang (Автор), Minghui Zhang (Автор), Jiade Li (Автор), Hongbo Ji (Автор), Shijun Li (Автор), Shucai Yang (Автор), Dandan Xu (Автор), Zhiwei Li (Автор), Tianzhen Wang (Автор), Yan He (Автор), Lei Zhang (Автор), Weiwei Yang (Автор), Ran Zhao (Автор), Dapeng Hao (Автор), Xiaobo Li (Автор)
• Формат: Книга
• Опубліковано: Elsevier, 2019-03-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Recent evidence shows that cyclic GMP-AMP synthase (cGAS)/stimulator of interferon (IFN) genes (STING) signaling is essential for antitumor immunity by inducing the production of type I IFN and thus activating both innate and adaptive immunity based on gene knockout mouse models. However, the extens...