An Analysis of the Expression and Association with Immune Cell Infiltration of the cGAS/STING Pathway in Pan-Cancer

• Main Authors: Xiang An (Author), Yuanyuan Zhu (Author), Tongsen Zheng (Author), Guangyu Wang (Author), Minghui Zhang (Author), Jiade Li (Author), Hongbo Ji (Author), Shijun Li (Author), Shucai Yang (Author), Dandan Xu (Author), Zhiwei Li (Author), Tianzhen Wang (Author), Yan He (Author), Lei Zhang (Author), Weiwei Yang (Author), Ran Zhao (Author), Dapeng Hao (Author), Xiaobo Li (Author)
• Format: Book
• Published: Elsevier, 2019-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Recent evidence shows that cyclic GMP-AMP synthase (cGAS)/stimulator of interferon (IFN) genes (STING) signaling is essential for antitumor immunity by inducing the production of type I IFN and thus activating both innate and adaptive immunity based on gene knockout mouse models. However, the extens...