Effect of meal timing on pharmacokinetics and pharmacodynamics of tegoprazan in healthy male volunteers

• Main Authors: Deok Y. Yoon (Author), Jung Sunwoo (Author), Naree Shin (Author), Ah R. Kim (Author), Bongtae Kim (Author), Geun S. Song (Author), In‐Jin Jang (Author), SeungHwan Lee (Author)
• Format: Book
• Published: Wiley, 2021-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Tegoprazan, a novel potassium‐competitive acid blocker, is used to treat acid‐related diseases. However, there is no information on the pharmacokinetic (PK) and pharmacodynamic (PD) profiles of the marketed dosage of tegoprazan under various meal timings in a fed and fasted state. The study...