Control of endothelial cell function and arteriogenesis by MEG3:EZH2 epigenetic regulation of integrin expression

• Main Authors: Hywel Dunn-Davies (Author), Tatiana Dudnakova (Author), Antonella Nogara (Author), Julie Rodor (Author), Anita C. Thomas (Author), Elisa Parish (Author), Philippe Gautier (Author), Alison Meynert (Author), Igor Ulitsky (Author), Paolo Madeddu (Author), Andrea Caporali (Author), Andrew Baker (Author), David Tollervey (Author), Tijana Mitić (Author)
• Format: Book
• Published: Elsevier, 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Epigenetic processes involving long non-coding RNAs regulate endothelial gene expression. However, the underlying regulatory mechanisms causing endothelial dysfunction remain to be elucidated. Enhancer of zeste homolog 2 (EZH2) is an important rheostat of histone H3K27 trimethylation (H3K27me3) that...