The Induction of Cyclooxygenase-2 in IL-1β-Treated Endothelial Cells is Inhibited by Prostaglandin E2 through cAMP

• Main Authors: Pravit Akarasereenont (Author), Kitirat Techatrisak (Author), Sirikul Chotewuttakorn (Author), Athiwat Thaworn (Author)
• Formato: Livro
• Publicado em: Hindawi Limited, 1999-01-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Prostaglandins (PGS) have numerous cardiovascular and inflammatory effects. Cyclooxygenase (COX), which exists as COX-1 and COX-2 isoforms, is the first enzyme in the pathway in which arachidonic acid is converted to PGs. Prostaglandin E2 (PGE2) exerts a variety of biological activities for the main...