Dexamethasone Administration in Mice Leads to Less Body Weight Gain over Time, Lower Serum Glucose, and Higher Insulin Levels Independently of NRF2

• Main Authors: Fotini Filippopoulou (Author), George I. Habeos (Author), Vagelis Rinotas (Author), Antonia Sophocleous (Author), Gerasimos P. Sykiotis (Author), Eleni Douni (Author), Dionysios V. Chartoumpekis (Author)
• Format: Book
• Published: MDPI AG, 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Glucocorticoids are used widely on a long-term basis in autoimmune and inflammatory diseases. Their adverse effects include the development of hyperglycemia and osteoporosis, whose molecular mechanisms have been only partially studied in preclinical models. Both these glucocorticoid-induced patholog...