A dynamic interface between ubiquitylation and cAMP signaling

• Egile Nagusiak: Laura eRinaldi (Egilea), Maria eSepe (Egilea), Rossella eDelle Donne (Egilea), Antonio eFeliciello (Egilea)
• Formatua: Liburua
• Argitaratua: Frontiers Media S.A., 2015-09-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Phosphorylation waves drive the propagation of signals generated in response to hormones and growth factors in target cells. cAMP is an ancient second messenger implicated in key biological functions. In mammals, most of the effects elicited by cAMP are mediated by protein kinase A (PKA). Activation...