Lico A Causes ER Stress and Apoptosis via Up-Regulating miR-144-3p in Human Lung Cancer Cell Line H292

• Hoofdauteurs: Gang Chen (Auteur), Yueping Ma (Auteur), Zhe Jiang (Auteur), Yuan Feng (Auteur), Yueqing Han (Auteur), Yetian Tang (Auteur), Juan Zhang (Auteur), Hui Ni (Auteur), Xuezheng Li (Auteur), Ning Li (Auteur)
• Formaat: Boek
• Gepubliceerd in: Frontiers Media S.A., 2018-07-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

During our study on the bioactivities of natural flavonoids, we found that the total flavonoids (TFs) and the main constituent of it, licochalcone A (lico A), activated unfolded protein response (UPR) and induced autophagy and thereby apoptosis in H292 cells. MicroRNAs, such as the tumor repressor m...