Robust home brew fragment sizing assay for detection of MET exon 14 skipping mutation in non-small cell lung cancer patients in resource constrained community hospitals

• Main Authors: Anurag Mehta (Author), Shrinidhi Nathany (Author), Aanchal Chopra (Author), Sakshi Mattoo (Author), Dushyant Kumar (Author), Manoj Kumar Panigrahi (Author)
• Format: Book
• Published: Korean Society of Pathologists & the Korean Society for Cytopathology, 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background A mutation/deletion involving donor or acceptor sites for exon 14 results in splicing out of exon 14 of the mesenchymal epithelial transition (MET) gene and is known as "MET exon 14 skipping" (ΔMET14). The two recent approvals with substantial objective responses and improved pr...