Exploring the Mechanism of Total Flavonoids of Drynariae Rhizoma to Improve Large Bone Defects by Network Pharmacology and Experimental Assessment

• Main Authors: Weipeng Sun (Author), Minying Li (Author), Lei Xie (Author), Zhexing Mai (Author), Yan Zhang (Author), Lieliang Luo (Author), Zijian Yan (Author), Zige Li (Author), Hang Dong (Author), Feng Huang (Author), Zhen Shen (Author), Ziwei Jiang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Drynariae Rhizoma (DR) has been demonstrated to be effective in promoting fracture healing in clinical use. In the study, we tried to predicate potential signaling pathways and active ingredients of DR via network pharmacology, uncover its regulation mechanism to improve large bone defects by in viv...