Increased circulating Tfh17 and PD-1+Tfh cells are associated with autoantibodies in Hashimoto's thyroiditis

• Main Authors: Jiwei Zhao (Author), Yanxia Chen (Author), Qing Zhao (Author), Jie Shi (Author), Wei Yang (Author), Zhongliang Zhu (Author), Wenge Yu (Author), Jinju Guan (Author), Yingxiang Song (Author), Hui Wu (Author), Weidong Jin (Author), Yonglie Zhou (Author), Jinlin Liu (Author)
• Format: Book
• Published: Taylor & Francis Group, 2018-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Hashimoto's thyroiditis (HT) is characterized by autoantibodies targeting the thyroid. Abnormal CD4+CXCR5+T cell levels were previously shown to be associated with HT. However, Tfh cells consist of heterogeneous subpopulations, and which T follicular helper (Tfh) cell subpopulation p...