Isotoosendanin exerts inhibition on triple-negative breast cancer through abrogating TGF-β-induced epithelial-mesenchymal transition via directly targeting TGFβR1

• প্রধান লেখক: Jingnan Zhang (লেখক), Ze Zhang (লেখক), Zhenlin Huang (লেখক), Manlin Li (লেখক), Fan Yang (লেখক), Zeqi Wu (লেখক), Qian Guo (লেখক), Xiyu Mei (লেখক), Bin Lu (লেখক), Changhong Wang (লেখক), Zhengtao Wang (লেখক), Lili Ji (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Elsevier, 2023-07-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

As the most aggressive breast cancer, triple-negative breast cancer (TNBC) is still incurable and very prone to metastasis. The transform growth factor β (TGF-β)-induced epithelial-mesenchymal transition (EMT) is crucially involved in the growth and metastasis of TNBC. This study reported that a nat...