Consideration of Metabolite Efflux in Radiolabelled Choline Kinetics
Hypoxia is a complex microenvironmental condition known to regulate choline kinase α (CHKA) activity and choline transport through transcription factor hypoxia-inducible factor-1α (HIF-1α) and, therefore, may confound the uptake of choline radiotracer [<sup>18</sup>F]fluoromethyl-[1,2-&l...
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MDPI AG,
2021-08-01T00:00:00Z.
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