Development of Novel Faster-Dissolving Microneedle Patches for Transcutaneous Vaccine Delivery

• Main Authors: Akihiko Ono (Author), Sayami Ito (Author), Shun Sakagami (Author), Hideo Asada (Author), Mio Saito (Author), Ying-Shu Quan (Author), Fumio Kamiyama (Author), Sachiko Hirobe (Author), Naoki Okada (Author)
• Format: Book
• Published: MDPI AG, 2017-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Microneedle (MN) patches are promising for transcutaneous vaccination because they enable vaccine antigens to physically penetrate the stratum corneum via low-invasive skin puncturing, and to be effectively delivered to antigen-presenting cells in the skin. In second-generation MN patches, the disso...