Repurposing Verapamil to Enhance Killing of T-ALL Cells by the mTOR Inhibitor Everolimus

Repurposing Verapamil to Enhance Killing of T-ALL Cells by the mTOR Inhibitor Everolimus

New therapies are needed for patients with T-cell lymphoblastic leukemia (T-ALL) who do not respond to standard chemotherapy. Our previous studies showed that the mTORC1 inhibitor everolimus increases reactive oxygen species (ROS) levels, decreases the levels of NADPH and glucose-6-phosphate dehydro...

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Main Authors: Micol Silic-Benussi (Author), Evgeniya Sharova (Author), Alberto Corradin (Author), Loredana Urso (Author), Vittoria Raimondi (Author), Ilaria Cavallari (Author), Barbara Buldini (Author), Samuela Francescato (Author), Sonia A. Minuzzo (Author), Donna M. D'Agostino (Author), Vincenzo Ciminale (Author)
Format: Book
Published: MDPI AG, 2023-03-01T00:00:00Z.
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