Using Machine Learning to Predict Synergistic Antimalarial Compound Combinations With Novel Structures

• Main Authors: Daniel J. Mason (Author), Richard T. Eastman (Author), Richard P. I. Lewis (Author), Ian P. Stott (Author), Rajarshi Guha (Author), Andreas Bender (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The parasite Plasmodium falciparum is the most lethal species of Plasmodium to cause serious malaria infection in humans, and with resistance developing rapidly novel treatment modalities are currently being sought, one of which being combinations of existing compounds. The discovery of combinations...