Making Sense of Antisense Oligonucleotide Therapeutics Targeting Bcl-2
The B-cell lymphoma 2 (Bcl-2) family, comprised of pro- and anti-apoptotic proteins, regulates the delicate balance between programmed cell death and cell survival. The Bcl-2 family is essential in the maintenance of tissue homeostasis, but also a key culprit in tumorigenesis. Anti-apoptotic Bcl-2,...
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MDPI AG,
2022-01-01T00:00:00Z.
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