Macrophage Infiltration Initiates RIP3/MLKL-Dependent Necroptosis in Paclitaxel-Induced Neuropathic Pain

• Váldodahkkit: Dongyang Ma (Dahkki), Xiuli Wang (Dahkki), Xin Liu (Dahkki), Zhao Li (Dahkki), Jiaxin Liu (Dahkki), Jing Cao (Dahkki), Guiying Wang (Dahkki), Yuexian Guo (Dahkki), Shuang Zhao (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Hindawi Limited, 2022-01-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Paclitaxel (PTX) is a commonly used antitumor drug. Approximately 80% of all patients receiving PTX chemotherapy develop chemotherapy-induced peripheral neuropathy (CIPN), limiting the use of PTX. Moreover, CIPN responds poorly to conventional analgesics. Experimental evidence suggests that the neur...