The paradigm of total body irradiation in acute lymphoblastic leukaemia: Therapeutic effectiveness versus the challenges of toxicity

• Main Authors: Carlos Echecopar (Author), Ismael del Val Rey (Author), Víctor Galán-Gómez (Author), Carlos González-Pérez (Author), Yasmina Mozo del Castillo (Author), Berta González Martínez (Author), Antonio Pérez-Martínez (Author)
• Format: Book
• Published: Elsevier, 2024-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Total body irradiation (TBI) is part of the myeloablative conditioning for hematopoietic stem cell transplantation (HSCT) in malignant hematologic disorders. This therapy has recently shown improved survival in acute lymphoblastic leukemia (ALL) compared to chemotherapy-based regimens....