Gastrodin attenuates diabetic cardiomyopathy characterized by myocardial fibrosis by inhibiting the KLK8-PAR1 signaling axis

• Main Authors: MingShan Zhang (Author), YuFei Zhang (Author), JingGang He (Author), XinRui Wang (Author), YinYin Wang (Author), LinYan Li (Author), Ling Tao (Author), Min Zhang (Author), Xiangchun Shen (Author)
• פורמט: ספר
• יצא לאור: BMC, 2024-11-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

Abstract Background Diabetic cardiomyopathy (DCM), characterized by myocardial fibrosis, is a major cause of mortality and morbidity in diabetic patients; the inhibition of cardiac fibrosis is a fundamental strategy for treating DCM. Gastrodin (GAS), a compound extracted from Gastrodia elata protect...