Unlocking the Potential of Camel Milk-Derived Exosomes as Novel Delivery Systems: Enhanced Bioavailability of ARV-825 PROTAC for Cancer Therapy

• Auteurs principaux: Aakash Nathani (Auteur), Mounika Aare (Auteur), Li Sun (Auteur), Arvind Bagde (Auteur), Yan Li (Auteur), Arun Rishi (Auteur), Mandip Singh (Auteur)
• Format: Livre
• Publié: MDPI AG, 2024-08-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

This study investigates the use of camel milk-derived exosomes (CMEs) as carriers for ARV-825, an anticancer agent targeting bromodomain-containing protein 4 (BRD4), in oral chemotherapy. CMEs were isolated and characterized, and ARV-825-loaded CME formulations were prepared and evaluated through va...