Unlocking the Potential of Camel Milk-Derived Exosomes as Novel Delivery Systems: Enhanced Bioavailability of ARV-825 PROTAC for Cancer Therapy

• Egile Nagusiak: Aakash Nathani (Egilea), Mounika Aare (Egilea), Li Sun (Egilea), Arvind Bagde (Egilea), Yan Li (Egilea), Arun Rishi (Egilea), Mandip Singh (Egilea)
• Formatua: Liburua
• Argitaratua: MDPI AG, 2024-08-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

This study investigates the use of camel milk-derived exosomes (CMEs) as carriers for ARV-825, an anticancer agent targeting bromodomain-containing protein 4 (BRD4), in oral chemotherapy. CMEs were isolated and characterized, and ARV-825-loaded CME formulations were prepared and evaluated through va...