Covalent Inhibition of the <i>Human</i> 20S Proteasome with Homobelactosin C Inquired by QM/MM Studies
20S proteasome is a main player in the protein degradation pathway in the cytosol, thus intervening in multiple pivotal cellular processes. Over the years the proteasome has emerged as a crucial target for the treatment of many diseases such as neurodegenerative diseases, cancer, autoimmune diseases...
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MDPI AG,
2022-04-01T00:00:00Z.
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