Revisiting Preclinical Observations of Several Histamine H3 Receptor Antagonists/Inverse Agonists in Cognitive Impairment, Anxiety, Depression, and Sleep-Wake Cycle Disorder

• Main Authors: Mera Alhusaini (Author), Nermin Eissa (Author), Ali K. Saad (Author), Rami Beiram (Author), Bassem Sadek (Author)
• Format: Bog
• Udgivet: Frontiers Media S.A., 2022-06-01T00:00:00Z.
• Fag: article
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A relationship appears to exist between dysfunction of brain histamine (HA) and various neuropsychiatric brain disorders. The possible involvement of brain HA in neuropathology has gained attention recently, and its role in many (patho)physiological brain functions including memory, cognition, and s...