Therapeutic Drug Monitoring of Tacrolimus-Personalized Therapy in Heart Transplantation: New Strategies and Preliminary Results in Endomyocardial Biopsies

• প্রধান লেখক: Simona De Gregori (লেখক), Annalisa De Silvestri (লেখক), Barbara Cattadori (লেখক), Andrea Rapagnani (লেখক), Riccardo Albertini (লেখক), Elisa Novello (লেখক), Monica Concardi (লেখক), Eloisa Arbustini (লেখক), Carlo Pellegrini (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: MDPI AG, 2022-06-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Tacrolimus (TAC) is an immunosuppressant drug approved both in the US and in the EU, widely used for the prophylaxis of organ rejection after transplantation. This is a critical dose drug: low levels in whole blood can lead to low exposure and a high risk of acute rejection, whereas overexposure put...