Development of Halogenated-Chalcones Bearing with Dimethoxy Phenyl Head as Monoamine Oxidase-B Inhibitors

• Asıl Yazarlar: Nisha Abdul Rehuman (Yazar), Jong Min Oh (Yazar), Mohamed A. Abdelgawad (Yazar), Eman A. M. Beshr (Yazar), Mohammed A. S. Abourehab (Yazar), Nicola Gambacorta (Yazar), Orazio Nicolotti (Yazar), Rakesh Kumar Jat (Yazar), Hoon Kim (Yazar), Bijo Mathew (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: MDPI AG, 2022-09-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Two series of dimethoxy-halogenated chalcones (<b>DM1</b>-<b>DM20</b>) were synthesized and tested for their ability to inhibit monoamine oxidase (MAOs). Compound <b>DM2</b> exhibited the most significant inhibition against MAO-B with an IC₅₀...