Improvement of solubility, dissolution, and bioavailability of phenytoin intercalated in Mg-Al layered double hydroxide

• Main Authors: Rehab Anwar Bakr (Author), Sabna Kotta (Author), Hibah Mubarak Aldawsari (Author), Lubna Y. Ashri (Author), Shaimaa M. Badr-Eldin (Author), Heba Eltahir (Author), Sameh A. Ahmed (Author), Yaser M. Alahmadi (Author), Mekky Abouzied (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Layered double hydroxides (LDHs) are highly effective drug delivery systems, owing to their capacity to intercalate or adsorb biomaterials, flexible structure, swelling property, high stability, good biocompatibility, and ease of synthesis. Phenytoin (PHT) is an antiseizure BCS (Biopharmaceutics Cla...