Tranilast Suppresses the Disease Development of the Adjuvant- and Streptococcal Cell Wall-Induced Arthritis in Rats

• المؤلفون الرئيسيون: Toshiaki Nagate (مؤلف), Toru Tamura (مؤلف), Fumiyasu Sato (مؤلف), Junji Kuroda (مؤلف), Jun Nakayama (مؤلف), Nobuo Shibata (مؤلف)
• التنسيق: كتاب
• منشور في: Elsevier, 2007-01-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

This study explores the effects of the anti-allergic and anti-fibrotic agent tranilast on adjuvant- and streptococcal cell wall-induced arthritis in rats, animal models of rheumatoid arthritis in humans. Tranilast (150 or 300 mg/kg, twice daily) or vehicle only was administered orally to the two art...