Senescent cell depletion alleviates obesity-related metabolic and cardiac disorders

• Main Authors: Tábatha de Oliveira Silva (Author), Guilherme Lunardon (Author), Caroline A. Lino (Author), Amanda de Almeida Silva (Author), Shiju Zhang (Author), Maria Cláudia Costa Irigoyen (Author), Yao Wei Lu (Author), John D. Mably (Author), Maria Luiza M. Barreto-Chaves (Author), Da-Zhi Wang (Author), Gabriela P. Diniz (Author)
• Format: Book
• Published: Elsevier, 2025-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Obesity is a major contributor to metabolic and cardiovascular disease. Although senescent cells have been shown to accumulate in adipose tissue, the role of senescence in obesity-induced metabolic disorders and in cardiac dysfunction is not yet clear; therefore, the therapeutic potential of managin...