Vitamin B6 inhibits activity of Helicobacter pylori adenylosuccinate synthetase and growth of reference and clinical, antibiotic-resistant H. pylori strains

• Main Authors: Marta Ilona Wojtyś (Author), Weronika Maksymiuk (Author), Marta Narczyk (Author), Ante Bubić (Author), Ivana Leščić Ašler (Author), Paweł Krzyżek (Author), Grażyna Gościniak (Author), Elżbieta Katarzyna Jagusztyn-Krynicka (Author), Agnieszka Bzowska (Author)
• Format: Book
• Published: Taylor & Francis Group, 2024-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The current therapies against gastric pathogen Helicobacter pylori are ineffective in over 20% of patients. Enzymes belonging to the purine salvage pathway are considered as novel drug targets in this pathogen. Therefore, the main aim of the current study was to determine the antibacterial activity...