Experimental Human Cell and Tissue Models of Pemphigus

• Главные авторы: Gerda van der Wier (Автор), Hendri H. Pas (Автор), Marcel F. Jonkman (Автор)
• Формат: ‌
• Опубликовано: Hindawi Limited, 2010-01-01T00:00:00Z.
• Предметы: article
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Pemphigus is a chronic mucocutaneous autoimmune bullous disease that is characterized by loss of cell-cell contact in skin and/or mucous membranes. Past research has successfully identified desmosomes as immunological targets and has demonstrated that acantholysis is initiated through direct binding...