Transcriptome-Based Network Analysis Reveals Hirudin Potentiates Anti-Renal Fibrosis Efficacy in UUO Rats

• Main Authors: Hang-Xing Yu (Author), Wei Lin (Author), Kang Yang (Author), Li-Juan Wei (Author), Jun-Li Chen (Author), Xin-Yue Liu (Author), Ke Zhong (Author), Xin Chen (Author), Ming Pei (Author), Hong-Tao Yang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Hirudin has been widely used in the treatment of antifibrosis. Previous studies have shown that hirudin can effectively improve the clinical remission rate of chronic kidney disease. However, the mechanism of its renal protection has not been systematically investigated.Methods: In this...