Tofacitinib Loaded Squalenyl Nanoparticles for Targeted Follicular Delivery in Inflammatory Skin Diseases

• Váldodahkkit: Rebekka Christmann (Dahkki), Duy-Khiet Ho (Dahkki), Jenny Wilzopolski (Dahkki), Sangeun Lee (Dahkki), Marcus Koch (Dahkki), Brigitta Loretz (Dahkki), Thomas Vogt (Dahkki), Wolfgang Bäumer (Dahkki), Ulrich F. Schaefer (Dahkki), Claus-Michael Lehr (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: MDPI AG, 2020-11-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Tofacitinib (TFB), a Janus kinase inhibitor, has shown excellent success off-label in treating various dermatological diseases, especially alopecia areata (AA). However, TFB's safe and targeted delivery into hair follicles (HFs) is highly desirable due to its systemic adverse effects. Nanoparti...