Analysis of Inflammatory Mediator Profiles in Sepsis Patients Reveals That Extracellular Histones Are Strongly Elevated in Nonsurvivors

• Main Authors: Tanja Eichhorn (Author), Ingrid Linsberger (Author), Lucia Lauková (Author), Carla Tripisciano (Author), Birgit Fendl (Author), René Weiss (Author), Franz König (Author), Gerhard Valicek (Author), Georg Miestinger (Author), Christoph Hörmann (Author), Viktoria Weber (Author)
• Format: Book
• Published: Hindawi Limited, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The timely recognition of sepsis and the prediction of its clinical course are challenging due to the complex molecular mechanisms leading to organ failure and to the heterogeneity of sepsis patients. Treatment strategies relying on a "one-fits-all" approach have failed to reduce mortality...