Pyroptosis in the Initiation and Progression of Atherosclerosis

• Main Authors: Zhengtao Qian (Author), Yilin Zhao (Author), Chuandan Wan (Author), Yimai Deng (Author), Yaoyao Zhuang (Author), Yeqiong Xu (Author), Yanping Zhu (Author), Shourong Lu (Author), Zhengyang Bao (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Pyroptosis, a newly discovered form of programmed cell death, is characterized by cell swelling, the protrusion of large bubbles from the plasma membrane and cell lysis. This death pathway is mediated by the pore formation of gasdermin D (GSDMD), which is activated by human caspase-1/caspase-4/caspa...