Metabolic syndrome and extensive adipose tissue inflammation in morbidly obese Göttingen minipigs

• Main Authors: Simone Renner (Author), Andreas Blutke (Author), Britta Dobenecker (Author), Georg Dhom (Author), Timo D. Müller (Author), Brian Finan (Author), Christoffer Clemmensen (Author), Maren Bernau (Author), Istvan Novak (Author), Birgit Rathkolb (Author), Steffanie Senf (Author), Susanne Zöls (Author), Mirjam Roth (Author), Anna Götz (Author), Susanna M. Hofmann (Author), Martin Hrabĕ de Angelis (Author), Rüdiger Wanke (Author), Ellen Kienzle (Author), Armin M. Scholz (Author), Richard DiMarchi (Author), Mathias Ritzmann (Author), Matthias H. Tschöp (Author), Eckhard Wolf (Author)
• Format: Book
• Published: Elsevier, 2018-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: The worldwide prevalence of obesity has increased to 10% in men and 15% in women and is associated with severe comorbidities such as diabetes, cancer, and cardiovascular disease. Animal models of obesity are central to experimental studies of disease mechanisms and therapeutic strategies....