Pharmacogenetic Approaches to Enhancing Efficacy and Safety of Statins as Illustrated by the Example of Atorvastatin

• Autori principali: R. Ye. Kazakov (Autore), O. A. Checha (Autore), I. A. Mazerkina (Autore), E. Yu. Demchenkova (Autore), T. A. Aleksandrova (Autore), V. A. Evteev (Autore), S. A. Belkov (Autore), A. B. Prokofiev (Autore)
• Natura: Libro
• Pubblicazione: Ministry of Health of the Russian Federation, Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products», 2020-03-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Statins are efficacious lipid-lowering drugs used for prevention of cardiovascular complications in patients with high blood cholesterol. The efficacy and safety of this group of drugs is largely determined by genetic factors. The aim of the study was to analyse the effect of gene polymorphisms on t...