Placental mesenchymal stem cells ameliorate NLRP3 inflammasome-induced ovarian insufficiency by modulating macrophage M2 polarization

• Egile Nagusiak: Dongmei Chen (Egilea), Na Hu (Egilea), Shasha Xing (Egilea), Li Yang (Egilea), Feiyan Zhang (Egilea), Songlin Guo (Egilea), Shudan Liu (Egilea), Xiaona Ma (Egilea), Xueyun Liang (Egilea), Huiming Ma (Egilea)
• Formatua: Liburua
• Argitaratua: BMC, 2023-03-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Abstract Background Premature ovarian insufficiency (POI) is a common clinical problem, however, there are currently no effective therapies. Pyroptosis induced by the NLRP3 inflammasome is considered a possible mechanism of POI. Placental mesenchymal stem cells (PMSCs) have excellent immunomodulator...