Population Pharmacokinetics of Remimazolam in Procedural Sedation With Nonhomogeneously Mixed Arterial and Venous Concentrations

• Main Authors: Jie Zhou (Author), Laura Curd (Author), Lauren L. Lohmer (Author), Joachim Ossig (Author), Frank Schippers (Author), Thomas Stoehr (Author), Virginia Schmith (Author)
• Format: Book
• Published: Wiley, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Remimazolam is an ultra‐short acting benzodiazepine under development for procedural sedation and general anesthesia. Population pharmacokinetic analysis (PopPK) was conducted for remimazolam with arterial and venous samples previously, but results were limited by arterial‐venous concentration diffe...